C9orf117 antibody (Biotin)

Catalog No. ABIN1403053

Product Details anti-C9orf117 Antibody (Biotin)

Target: C9orf117 (Chromosome 9 Open Reading Frame 117 (C9orf117))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C9orf117 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf117

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for C9orf117

Target: C9orf117 (Chromosome 9 Open Reading Frame 117 (C9orf117))

Alternative Name: C9orf117 (C9orf117 Products)

Synonyms: MGC145683 antibody, cilia and flagella associated protein 157 antibody, CFAP157 antibody, cfap157 antibody, Cfap157 antibody

Background:

Synonyms: Chromosome 9 open reading frame 117, Hypothetical protein LOC286207, CI117_HUMAN.

Background: C9orf117 is a 520 amino acid protein that exists as two alternatively spliced isoforms. The gene encoding C9orf117 maps to human chromosome 9q34.11. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Gene ID: 286207