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INIP antibody (AA 1-50) (Biotin)

INIP Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1403029
  • Target See all INIP Antibodies
    INIP (INTS3 and NABP Interacting Protein (INIP))
    Binding Specificity
    AA 1-50
    Reactivity
    Human, Mouse, Rat
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INIP antibody is conjugated to Biotin
    Application
    • 14
    • 13
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SOSSC/C9orf80
    Isotype
    IgG
    Top Product
    Discover our top product INIP Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    INIP (INTS3 and NABP Interacting Protein (INIP))
    Alternative Name
    SOSSC (INIP Products)
    Synonyms
    C8H9orf80 antibody, C9orf80 antibody, SSBIP1 antibody, INIP antibody, HSPC043 antibody, MISE antibody, SOSSC antibody, hSSBIP1 antibody, 1110054O05Rik antibody, 2610312O17Rik antibody, AA399876 antibody, Ssbip1 antibody, SOSS-C antibody, ssbip1 antibody, zgc:56259 antibody, zgc:86662 antibody, c9orf80 antibody, hspc043-a antibody, mise antibody, sossc antibody, ci080 antibody, INTS3 and NABP interacting protein antibody, ints3 and nabp interacting protein antibody, INTS3 and NABP interacting protein S homeolog antibody, INIP antibody, Inip antibody, inip antibody, inip.S antibody
    Background

    Synonyms: INIP, Chromosome 9 open reading frame 80, hSSBIP1, MISE, RP11-276E15.2, Sensor of single-strand DNA complex subunit C, Sensor of ssDNA subunit C, Single-stranded DNA-binding protein-interacting protein 1, SOSS C, SOSS complex subunit C, SOSS-C, SOSSC, SOSSC_HUMAN, SSB-interacting protein 1, Ssbip1, C9orf80, INTS3- and NABP-interacting protein

    Background: The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.

    Gene ID
    58493
    UniProt
    Q9NRY2
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