HSPB7 antibody (AA 135-170) (AbBy Fluor® 350)
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- Target See all HSPB7 Antibodies
- HSPB7 (Heat Shock 27kDa Protein Family, Member 7 (Cardiovascular) (HSPB7))
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Binding Specificity
- AA 135-170
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HSPB7 antibody is conjugated to AbBy Fluor® 350
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HSPB7/cvHSP
- Isotype
- IgG
- Top Product
- Discover our top product HSPB7 Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- HSPB7 (Heat Shock 27kDa Protein Family, Member 7 (Cardiovascular) (HSPB7))
- Alternative Name
- HSPB7 (HSPB7 Products)
- Synonyms
- hspb7 antibody, MGC83758 antibody, HSPB7 antibody, cvhsp antibody, cvHSP antibody, 27kDa antibody, Hsp25-2 antibody, cvHsp antibody, heat shock protein family B (small) member 7 L homeolog antibody, heat shock protein family B (small) member 7 antibody, heat shock protein family, member 7 (cardiovascular) antibody, hspb7.L antibody, HSPB7 antibody, hspb7 antibody, Hspb7 antibody
- Background
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Synonyms: cvHSP, Heat shock protein beta-7, HspB7, Cardiovascular heat shock protein
Background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the small HSPs, the immunophilins and the HSP 110 family. HSPB7 (heat shock 27 kDa protein family, member 7), also known as cvHSP (cardiovascular heat shock protein) or Heat shock protein beta-7, is a member of the small HSP (sHSP) family expressed in heart and skeletal muscle. Members of the sHSP family contain a conserved C-terminal ?crystallin domain and typically function in homo- or heteromeric complexes. The sHSPs bind to denatured proteins and are responsible for preventing the aggregation of these proteins. In response to muscle fiber transformation and in muscular dystrophy, the expression levels of HSPB7 are drastically increased, suggesting that HSPB7 may be a useful target in therapeutic strategies for preventing age-related muscle wasting.
- Gene ID
- 27129
- UniProt
- Q9UBY9
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