Carkd antibody (AbBy Fluor® 488)
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- Target See all Carkd Antibodies
- Carkd (Carbohydrate Kinase Domain Containing (Carkd))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Carkd antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CARKD
- Isotype
- IgG
- Top Product
- Discover our top product Carkd Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Carkd (Carbohydrate Kinase Domain Containing (Carkd))
- Alternative Name
- CARKD (Carkd Products)
- Synonyms
- FLJ10769 antibody, DKFZp469O2314 antibody, LP3298 antibody, 0710008K08Rik antibody, 2810407E01Rik antibody, RGD1562691 antibody, NAD(P)HX dehydratase antibody, ATP-dependent (S)-NAD(P)H-hydrate dehydratase antibody, similar to S. cerevisiae YKL151C antibody, NAXD antibody, naxd antibody, Naxd antibody, R107.2 antibody, CaO19.11002 antibody
- Background
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Synonyms: Carbohydrate kinase domain containing, carbohydrate kinase domain-containing protein, FLJ10769, LP3298, NNRD_HUMAN.
Background: CARKD is a 347 amino acid protein that belongs to the YjeF family and exists as three alternatively spliced isoforms. Containing one YjeF C-terminal domain, CARKD is encoded by a gene that maps to human chromosome 13q34. Chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
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