DCAF12 antibody (AbBy Fluor® 488)
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- Target See all DCAF12 Antibodies
- DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DCAF12 antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DCAF12/WDR40A
- Isotype
- IgG
- Top Product
- Discover our top product DCAF12 Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))
- Alternative Name
- DCAF12 (DCAF12 Products)
- Synonyms
- CT102 antibody, KIAA1892 antibody, TCC52 antibody, WDR40A antibody, 1500001L20Rik antibody, 5830424K06Rik antibody, AA420338 antibody, AI851081 antibody, Wdr40a antibody, wdr40a antibody, wu:fb93d04 antibody, zgc:154031 antibody, wdr40b antibody, dcaf12 antibody, wdr40a-a antibody, DDB1 and CUL4 associated factor 12 antibody, DDB1 and CUL4 associated factor 12 L homeolog antibody, DCAF12 antibody, Dcaf12 antibody, dcaf12 antibody, dcaf12.L antibody
- Background
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Synonyms: cancer/testis antigen 102, Centrosome-related protein TCC52, CT102, DCA12_HUMAN, DCAF12, DDB1- and CUL4-associated factor 12, TCC52, Testis cancer centrosome-related protein, WD repeat domain 40A, WD repeat-containing protein 40A, WDR40A.
Background: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR40A (WD-repeat-containing protein 40A), also known as DDB1- CUL4-associated factor 12, is a 453 amino acid cytoplasmic protein that contains four WD-repeats. WDR40A is highly expressed in some cancer cell lines, lung cancer tissues and normal testis. A probable substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex, WRD40A is suggested to interact with DDB1. WDR40A is encoded by a gene mapping to human chromosome 9p13.3. Human chromosome 9 houses over 900 genes and comprises nearly 4 % of the human genome.
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