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CAF1p55 antibody (AbBy Fluor® 647)

CAF1 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 647
Catalog No. ABIN1402452
  • Target See all CAF1p55 (CAF1) products
    CAF1p55 (CAF1) (Chromatin Assembly Factor 1 Subunit (CAF1))
    Reactivity
    Human, Mouse, Rat
    Host
    • 14
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CAF1p55 antibody is conjugated to AbBy Fluor® 647
    Application
    • 14
    • 12
    • 3
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CAF1p55
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CAF1p55 (CAF1) (Chromatin Assembly Factor 1 Subunit (CAF1))
    Alternative Name
    CAF1p55 (CAF1 Products)
    Background

    Synonyms: Caf 1, CAF-1, CAF-1 P55 subunit, CAF1 p55 subunit, CAF1A, CAF1P55, chaf1b, Chromatin assembly factor 1 p55 subunit, Chromatin assembly factor 1 p60 subunit, chromatin assembly factor 1 subunit, Chromatin assembly factor I, dCAF-1, dCAF1, Human chromatin assembly factor-I p55 subunit, Nucleosome remodeling factor 55 kDa subunit, NURF 55, NURF-55, p55, Probable histone binding protein Caf1, VPRBP_HUMAN.

    Background: P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.

    Gene ID
    9730
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