PSMA7 antibody (AbBy Fluor® 555)
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- Target See all PSMA7 Antibodies
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMA7 antibody is conjugated to AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 7
- Isotype
- IgG
- Top Product
- Discover our top product PSMA7 Primary Antibody
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
- Abstract
- PSMA7 Products
- Synonyms
- C6 antibody, HSPC antibody, RC6-1 antibody, XAPC7 antibody, C6-I antibody, DDBDRAFT_0185059 antibody, DDBDRAFT_0217080 antibody, DDB_0185059 antibody, DDB_0217080 antibody, hspc antibody, rc6-1 antibody, xapc7 antibody, psma7 antibody, psma4-B antibody, proteasome subunit alpha 7 antibody, proteasome (prosome, macropain) subunit, alpha type 7 antibody, 20S proteasome subunit alpha-7 antibody, proteasome subunit alpha 7 S homeolog antibody, proteasome subunit alpha 7 L homeolog antibody, PSMA7 antibody, Psma7 antibody, psmA7 antibody, psma7 antibody, psma7.S antibody, psma7.L antibody
- Background
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Synonyms: C6 antibody HSPC, Proteasome prosome macropain subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, Proteasome subunit alpha type-7, Proteasome subunit RC6 1, Proteasome subunit RC6-1, Proteasome subunit XAPC7, PSA7_HUMAN, PSMA7, RC6 1, XAPC7.
Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
- Gene ID
- 5688
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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