PSMA6 antibody (Biotin)

Catalog No. ABIN1402249

Product Details anti-PSMA6 Antibody (Biotin)

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA6 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Proteasome 20S alpha 6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PSMA6

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Abstract: PSMA6 Products

Synonyms: IOTA antibody, PROS27 antibody, p27K antibody, psma6 antibody, psma6b antibody, zgc:91778 antibody, proteasome subunit alpha 6 antibody, proteasome (prosome, macropain) subunit, alpha type 6 antibody, proteasome subunit alpha 6a antibody, proteasome subunit alpha 6 L homeolog antibody, proteasome subunit alpha 6, like antibody, PSMA6 antibody, Psma6 antibody, psma6a antibody, psma6.L antibody, psma6l antibody

Background:

Synonyms: 27 kDa prosomal protein, HC2, IOTA, Macropain iota chain, Macropain subunit iota, Multicatalytic endopeptidase complex iota chain, p27K, PROS 27, PROS27, Prosomal P27K protein, Proteasome prosome macropain subunit alpha type 6, Proteasome iota chain, Proteasome subunit alpha type 1, Proteasome subunit alpha type 6, Proteasome subunit iota, PSMA6, PSA6_HUMAN.

Background: The gene encodes a 246-amino acid polypeptide containing an RNA binding motif, a putative nuclear localization signal, and phosphorylation sites. The alpha subunits comprises the outer rings of the proteasome. Some alpha subunits contain a functional nuclear localization signal, proteasomes are found in both the nuclear and cytoplasmic compartments of the cell. Alpha subunits may constitute a physical barrier that limits access of cytosolic proteins into the inner proteolytic chamber.

Gene ID: 5687

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA