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SH3RF2 antibody (AbBy Fluor® 350)

SH3RF2 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN1401597
  • Target See all SH3RF2 Antibodies
    SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))
    Reactivity
    Human, Mouse, Rat
    Host
    • 28
    • 2
    Rabbit
    Clonality
    • 28
    • 2
    Polyclonal
    Conjugate
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH3RF2 antibody is conjugated to AbBy Fluor® 350
    Application
    • 30
    • 14
    • 12
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RNF158
    Isotype
    IgG
    Top Product
    Discover our top product SH3RF2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))
    Alternative Name
    RNF158 (SH3RF2 Products)
    Synonyms
    MGC81405 antibody, SH3RF2 antibody, HEPP1 antibody, POSHER antibody, PPP1R39 antibody, RNF158 antibody, 2310046K19 antibody, 9130023G24Rik antibody, AI452083 antibody, Ppp1r39 antibody, Posh2 antibody, SH3 domain containing ring finger 2 antibody, SH3 domain containing ring finger 2 S homeolog antibody, SH3RF2 antibody, sh3rf2.S antibody, sh3rf2 antibody, Sh3rf2 antibody
    Background

    Synonyms: Heart protein phosphatase 1-binding protein, HEPP1, Putative E3 ubiquitin protein ligase SH3RF2, Putative E3 ubiquitin-protein ligase SH3RF2, RING finger protein 158, SH3 domain containing RING finger protein 2, SH3 domain-containing RING finger protein 2, SH3R2_HUMAN, Sh3rf2.

    Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. SH3RF2 (SH3 domain containing ring finger 2), also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains. Via its RING-type zinc finger domain, SH3RF2 binds an E2 ubiquitin-conjugating enzyme. This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Due to alternative splicing events, SH3RF2 is expressed as two different isoforms.

    Gene ID
    153769
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