IGSF3 antibody (AbBy Fluor® 350)

Catalog No. ABIN1401393

Product Details anti-IGSF3 Antibody (AbBy Fluor® 350)

Target: IGSF3 (Immunoglobulin Superfamily, Member 3 (IGSF3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF3 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IGSF3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IGSF3

Target: IGSF3 (Immunoglobulin Superfamily, Member 3 (IGSF3))

Alternative Name: IGSF3 (IGSF3 Products)

Synonyms: igsf3 antibody, EWI-3 antibody, V8 antibody, 1700016K10Rik antibody, 2810035F16Rik antibody, 4833439O17Rik antibody, mKIAA0466 antibody, immunoglobulin superfamily member 3 antibody, immunoglobulin superfamily, member 3 antibody, IGSF3 antibody, igsf3.S antibody, igsf3 antibody, Igsf3 antibody

Background:

Synonyms: EWI 3, EWI3, Glu Trp Ile EWI mot containing protein 3, Immunoglobin superfamily member 3, Immunoglobulin superfamily member 3, KIAA0466, MGC117164, V8 antibody, IGSF3_HUMAN.

Background: IGSF3, also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32 % identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function. Based on its subcellular localization and the presence of the eight Ig domains, IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule.

Gene ID: 3321

UniProt: O75054