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SLFN14 antibody (AbBy Fluor® 555)

SLFN14 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 555
Catalog No. ABIN1401359
  • Target See all SLFN14 products
    SLFN14 (Schlafen Family Member 14 (SLFN14))
    Reactivity
    Human, Mouse, Rat
    Host
    • 16
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLFN14 antibody is conjugated to AbBy Fluor® 555
    Application
    • 16
    • 12
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SLFN14
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SLFN14 (Schlafen Family Member 14 (SLFN14))
    Alternative Name
    SLFN14 (SLFN14 Products)
    Synonyms
    LRRGT00163 antibody, Gm20 antibody, Slfn14-ps antibody, schlafen family member 14 antibody, protein SLFN14 antibody, schlafen family member 11 antibody, schlafen 14 antibody, Slfn14 antibody, LOC491140 antibody, SLFN14 antibody, SLFN11 antibody, LOC100021434 antibody, LOC100358198 antibody
    Background

    Synonyms: Schlafen family member 14, SLFN14, SLN14_HUMAN.

    Background: Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.

    Gene ID
    342618
    UniProt
    P0C7P3
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