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TRIM50 antibody (Biotin)

TRIM50 Reactivity: Human, Rat, Mouse WB, IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1401133
  • Target See all TRIM50 Antibodies
    TRIM50 (Tripartite Motif Containing 50 (TRIM50))
    Reactivity
    • 32
    • 16
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 32
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM50 antibody is conjugated to Biotin
    Application
    • 32
    • 13
    • 13
    • 13
    • 12
    • 4
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TRIM50
    Isotype
    IgG
    Top Product
    Discover our top product TRIM50 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    TRIM50 (Tripartite Motif Containing 50 (TRIM50))
    Alternative Name
    TRIM50 (TRIM50 Products)
    Synonyms
    TRIM50A antibody, tripartite motif containing 50 antibody, tripartite motif-containing 50 antibody, TRIM50 antibody, Trim50 antibody
    Background

    Synonyms: E3 ubiquitin ligase, E3 ubiquitin protein ligase TRIM50, TRIM50A, Tripartite mot containing protein 50, tripartite mot protein 50A, tripartite mot-containing 50A, TRI50_HUMAN.

    Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM50 (tripartite motif containing 50), also known as TRIM50A or E3 ubiquitin-protein ligase TRIM50, is a 487 amino acid cytoplasmic protein that functions as an E3 ubiquitin-protein ligase. Containing one RING-type zinc finger, a B30.2/SPRY domain and a single B box-type zinc finger, TRIM50 belongs to the TRIM/RBCC family and undergoes post-translational auto-ubiquitination. TRIM50 exists as two alternatively spliced isoforms, designated TRIM50 alpha and TRIM50 beta, and has the ability to form dimers and trimers. The gene encoding TRIM50 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

    Gene ID
    135892
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