UBOX5 antibody (AbBy Fluor® 350)

Catalog No. ABIN1401093

Product Details anti-UBOX5 Antibody (AbBy Fluor® 350)

Target: UBOX5 (U-Box Domain Containing 5 (UBOX5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBOX5 antibody is conjugated to AbBy Fluor® 350

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBOX5/RNF37

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for UBOX5

Target: UBOX5 (U-Box Domain Containing 5 (UBOX5))

Alternative Name: UBOX5 (UBOX5 Products)

Synonyms: RGD1305440 antibody, 1500010O06Rik antibody, C330018L13Rik antibody, Rnf37 antibody, UIP5 antibody, Ubce7ip5 antibody, Ube7ip5 antibody, RNF37 antibody, UBCE7IP5 antibody, U-box domain containing 5 antibody, U-box domain containing 5 S homeolog antibody, U box domain containing 5 antibody, Ubox5 antibody, UBOX5 antibody, ubox5.S antibody

Background:

Synonyms: UIP5, UIP-5, UIP 5, RING finger protein 37, RNF37, U-box domain containing 5, U-box domain-containing protein 5, UBCE7IP5, ubiquitin conjugating enzyme 7 interacting protein 5, UBOX5, RNF37_HUMAN.

Background: The U-box domain is a modified RING finger motif that has been implicated in the ubiquitin/proteasome system. The ubiquitin-conjugating enzyme 7-interacting protein 5 (UIP5), also designated U-box domain-containing protein 5 or RING finger protein 37, contains 1 RING-type zinc finger and 1 U-box domain. UIP5 has been shown to interact with UBCH7, an enzyme that mediates selective degradation of abnormal proteins. The gene encoding UIP5 maps to chromosome 20, which houses over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Gene ID: 22888