ASB7 antibody (Biotin)

Catalog No. ABIN1401031

Product Details anti-ASB7 Antibody (Biotin)

Target: ASB7 (Ankyrin Repeat and SOCS Box Containing 7 (ASB7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB7 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ASB7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ASB7

Target: ASB7 (Ankyrin Repeat and SOCS Box Containing 7 (ASB7))

Alternative Name: ASB7 (ASB7 Products)

Synonyms: AI449039 antibody, Asb-7 antibody, D030055C23Rik antibody, asb7 antibody, zgc:77381 antibody, ASB-7 antibody, ankyrin repeat and SOCS box containing 7 antibody, ankyrin repeat and SOCS box-containing 7 antibody, ankyrin repeat and SOCS box containing 7 L homeolog antibody, ASB7 antibody, Asb7 antibody, asb7.L antibody, asb7 antibody

Background:

Synonyms: Ankyrin repeat and SOCS box containing protein 7, ASB 7, ASB-7, ASB7_HUMAN.

Background: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-7 (ankyrin repeat and SOCS box-containing 7) is a 318 amino acid protein that contains one SOCS box domain and seven ANK repeats and belongs to the ASB family. Existing as multiple alternatively spliced isoforms, ASB-7 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins.

Gene ID: 140460