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HDGFRP2 antibody (AbBy Fluor® 488)

HDGFRP2 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1400674
  • Target See all HDGFRP2 Antibodies
    HDGFRP2 (Hepatoma-Derived Growth Factor-Related Protein 2 (HDGFRP2))
    Reactivity
    Human, Mouse, Rat
    Host
    • 33
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HDGFRP2 antibody is conjugated to AbBy Fluor® 488
    Application
    • 33
    • 13
    • 12
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HRP2
    Isotype
    IgG
    Top Product
    Discover our top product HDGFRP2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HDGFRP2 (Hepatoma-Derived Growth Factor-Related Protein 2 (HDGFRP2))
    Alternative Name
    HRP2 (HDGFRP2 Products)
    Synonyms
    HDGF2 antibody, Hdgf2 antibody, hdgf2 antibody, hrp2 antibody, HRP-2 antibody, HDGF like 2 antibody, HDGF like 2 L homeolog antibody, HDGFL2 antibody, Hdgfl2 antibody, hdgfl2.L antibody
    Background

    Synonyms: HDGF-2, Hdgfrp2, HDGR2_HUMAN, Hepatoma-derived growth factor 2, Hepatoma-derived growth factor, Hepatoma-derived growth factor-related protein 2, heptoma derived growth factor related protein 2, HRP-2.

    Background: Hepatoma Derived Growth Factor (HDGF) is the original member of a family of polypeptides designated HDGF-related proteins (HRPs). HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. This nuclear targeted vascular smooth muscle cell mitogen (VSM) is a heparin-binding protein that is highly expressed in tumor cells where it stimulates proliferation. HDGF is also reported to be involved in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. During development, HDGF expression is high in the nucleus and cytoplasm of smooth muscle and endothelial cells. The HRP (HDGF related proteins) family contains four proteins, HRP-1, HRP-2, HRP-3 and HRP-4. HRP-1 and HRP-4 are only expressed in testis while HRP-2 is widely expressed in different tissues. HRP-3 can solely be found in the nervous system. Specifically it is strongly expressed in bulbus, olfactorius, piriform cotrex and amygdala complex while HRP-2 in brain is located in the the thalamus, prefrontal and parietal cortex, neurohypophysis, and the cerebellum. In the central nervous system, HRP proteins are play a role in neuron proliferation and cell survival.

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