PDZD7 antibody (AbBy Fluor® 647)

Catalog No. ABIN1400502

Product Details anti-PDZD7 Antibody (AbBy Fluor® 647)

Target: PDZD7 (PDZ Domain Containing 7 (PDZD7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZD7 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDZD7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDZD7

Target: PDZD7 (PDZ Domain Containing 7 (PDZD7))

Alternative Name: PDZD7 (PDZD7 Products)

Synonyms: PDZK7 antibody, Pdzk7 antibody, PDZD7 antibody, DKFZp459K1926 antibody, si:dkey-158p2.1 antibody, 9130207N01 antibody, EG435601 antibody, PDZ domain containing 7 antibody, PDZ domain containing 7a antibody, PDZD7 antibody, Pdzd7 antibody, pdzd7a antibody

Background:

Synonyms: PDZ domain containing 7, PDZK7, RP11-108L7.9, EG435601, OTTMUSP00000044305, 9130207N01, OTTMUSP00000044304, PDZD7_HUMAN.

Background: PDZK7, also known as PDZD7, is a 517 amino acid protein that contains two PDZ (DHR) domains. Encoded by a gene that maps to human chromosome 10q24.31, PDZK7 is conserved in dog, mouse and rat, and exists as three alternatively spliced isoforms. PDZK7 is known to interact with Harmonin, MASS1, USH1G and Usherin. Localizing to nucleus, PDZK7 is expressed in retinal pigment epithelium and inner ear. Biallelic inactivation of PDZK7 can cause non-syndromic hearing impairment and chromosomal aberrations, which are linked to non-syndromic sensorineural deafness. PDZK7 mutations are also linked to Usher syndrome, which is characterized by retinitis pigmentosa and sensorineural deafness, and Alzheimer disease. The gene that encodes PDZK7 maps to human chromosome 10q24.31.

Gene ID: 79955