EFHA1 antibody (AbBy Fluor® 350)

Catalog No. ABIN1400319

Product Details anti-EFHA1 Antibody (AbBy Fluor® 350)

Target: EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFHA1 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EFHA1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EFHA1

Target: EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))

Alternative Name: EFHA1 (EFHA1 Products)

Synonyms: 1110008L20Rik antibody, EFHA1 antibody, Efha1 antibody, RGD1309934 antibody, Smhs2 antibody, 4833427E09Rik antibody, AU041871 antibody, mitochondrial calcium uptake 2 antibody, MICU2 antibody, Micu2 antibody

Background:

Synonyms: EF-HA1, EF hand domain containing family member A1, EF hand domain family A1, EF hand domain family member A1, EFHA1 EF hand domain family member A1, FLJ25016, FLJ34588, Smhs2 homolog, 1110008L20Rik, EFHA1_HUMAN.

Background: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HA1 (EF-hand domain family, member A1) is a 434 amino acid protein that contains four EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. The gene encoding EF-HA1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4 % of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Gene ID: 221154