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ANKRD6 antibody (AbBy Fluor® 488)

ANKRD6 Reactivity: Human, Rat, Mouse WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1400242
  • Target See all ANKRD6 Antibodies
    ANKRD6 (Ankyrin Repeat Domain 6 (ANKRD6))
    Reactivity
    • 31
    • 16
    • 15
    • 2
    Human, Rat, Mouse
    Host
    • 30
    • 1
    Rabbit
    Clonality
    • 30
    • 1
    Polyclonal
    Conjugate
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ANKRD6 antibody is conjugated to AbBy Fluor® 488
    Application
    • 31
    • 13
    • 13
    • 12
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ANKRD6/Diversin
    Isotype
    IgG
    Top Product
    Discover our top product ANKRD6 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ANKRD6 (Ankyrin Repeat Domain 6 (ANKRD6))
    Alternative Name
    ANKRD6 (ANKRD6 Products)
    Synonyms
    ANKRD6 antibody, ankrd6 antibody, diversin antibody, si:dkey-181i3none antibody, ankyrin repeat domain 6 antibody, ankyrin repeat domain 6b antibody, ANKRD6 antibody, ankrd6b antibody, Ankrd6 antibody
    Background

    Synonyms: ANKRD 6, ankyrin repeat domain 6, ANKR6_HUMAN, Ankyrin repeat domain-containing protein 6, Diversin.

    Background: Diversin, also known as ANKRD6 (ankyrin repeat domain 6), is a 727 amino acid protein that contains eight ankyrin repeats and belongs to the ankyrin repeat domain protein family. Members of the ankyrin repeat domain family facilitate protein-protein interactions and function as adaptors of signaling pathways. Expressed in a developmentally-regulated manner and at highest levels in the brain, Diversin is believed to play a role in brain development. Via its ankyrin repeats, Diversin can directly interact with Dvl (dishevelled), an interaction that is essential for the activation of noncanonical Wnt signaling. In addition, Diversin contains a C-terminal domain that binds Axin/Conductin and a casein kinase-binding domain in its central region that specifically binds casein kinase I?. Through the action of these additional domains, Diversin may also facilitate canonical Wnt signaling. Due to alternative splicing events, three Diversin isoforms exist.

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