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MEPE antibody (AA 201-300) (AbBy Fluor® 647)

MEPE Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 647
Catalog No. ABIN1400190
  • Target See all MEPE Antibodies
    MEPE (Matrix Extracellular phosphoglycoprotein (MEPE))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reactivity
    • 22
    • 17
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 36
    • 2
    • 1
    Rabbit
    Clonality
    • 37
    • 2
    Polyclonal
    Conjugate
    • 17
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MEPE antibody is conjugated to AbBy Fluor® 647
    Application
    • 38
    • 19
    • 12
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MEPE
    Isotype
    IgG
    Top Product
    Discover our top product MEPE Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MEPE (Matrix Extracellular phosphoglycoprotein (MEPE))
    Alternative Name
    MEPE (MEPE Products)
    Synonyms
    OF45 antibody, OC-116 antibody, Of45 antibody, matrix extracellular phosphoglycoprotein antibody, matrix extracellular phosphoglycoprotein with ASARM motif (bone) antibody, MEPE antibody, Mepe antibody, LOC789774 antibody
    Background

    Synonyms: Matrix extracellular phosphoglycoprotein, MEPE, MEPE_HUMAN, OF45, Osteoblast/osteocyte factor 45.

    Background: MEPE is a 525 amino acid extracellular matrix protein. Expressed in osteocytes and brain, MEPE is a regulator of bone metabolism that is thought to mediate mineralization and demineralization within the osteocyte microenvironment. MEPE contains an RGD cell-attachment motif and shares molecular similarities with several dentin-bone extracellular matrix RGD-containing phosphoglycoproteins, including OPN (osteopontin) and DSP (dentin sialophosphoprotein). Via its ability to control bone mineralization, MEPE is associated with various developmental events such as skeletogenesis, bone regeneration and odontogenesis. MEPE is secreted in hypophosphatemic osteomalacia tumors, suggesting a possible role in the pathophysiology of bone-related cancers.

    Gene ID
    56955
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