GRAMD2 antibody (AA 151-250) (AbBy Fluor® 488)

Catalog No. ABIN1399834

Product Details anti-GRAMD2 Antibody (AbBy Fluor® 488)

Target: GRAMD2 (GRAM Domain Containing 2 (GRAMD2))

Binding Specificity: AA 151-250

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRAMD2 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRAMD2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GRAMD2

Target: GRAMD2 (GRAM Domain Containing 2 (GRAMD2))

Alternative Name: GRAMD2 (GRAMD2 Products)

Synonyms: BC064463 antibody, RGD1564007 antibody, Gramd2 antibody, GRAM domain containing 2 antibody, GRAM domain containing 2A antibody, Gramd2 antibody, GRAMD2A antibody, Gramd2a antibody

Background:

Synonyms: GRAM domain containing 2, GRAM domain containing protein 2, GRAMD 2, GRAM2_HUMAN.

Background: GRAMD2 is a 354 amino acid single-pass membrane protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 15q23. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3 % of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Gene ID: 196996