HAGHL antibody (AA 1-100) (AbBy Fluor® 488)

Catalog No. ABIN1398946

Product Details anti-HAGHL Antibody (AbBy Fluor® 488)

Target: HAGHL (Hydroxyacylglutathione Hydrolase-Like (HAGHL))

Binding Specificity: AA 1-100

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAGHL antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HAGHL

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HAGHL

Target: HAGHL (Hydroxyacylglutathione Hydrolase-Like (HAGHL))

Alternative Name: HAGHL (HAGHL Products)

Synonyms: 1500017E18Rik antibody, 2810014I23Rik antibody, C330022E15Rik antibody, hydroxyacylglutathione hydrolase-like antibody, hydroxyacylglutathione hydrolase like antibody, Haghl antibody, HAGHL antibody

Background:

Synonyms: HAGHL, HAGHL_HUMAN, Hydroxyacylglutathione hydrolase-like, Hydroxyacylglutathione hydrolase-like protein.

Background: The hydroxyacylglutathione hydrolase-like protein (HAGHL) is a 290 amino acid protein that belongs to the glyoxalase II family. HAGHL binds two zinc ions per subunit and acts as a hydrolase on ester bonds. The gene encoding HAGHL maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3 % of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Gene ID: 84264