LRRC41 antibody (AA 331-430) (FITC)

Catalog No. ABIN1398644

Product Details anti-LRRC41 Antibody (FITC)

Target: LRRC41 (Leucine Rich Repeat Containing 41 (LRRC41))

Binding Specificity: AA 331-430

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC41 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRRC41

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LRRC41

Target: LRRC41 (Leucine Rich Repeat Containing 41 (LRRC41))

Alternative Name: LRRC41 (LRRC41 Products)

Synonyms: LRRC41 antibody, MUF1 antibody, RP4-636H5.2 antibody, AA409966 antibody, AW555107 antibody, D630045E04Rik antibody, D730026A16Rik antibody, RGD1311221 antibody, MGC137526 antibody, leucine rich repeat containing 41 antibody, leucine-rich repeat-containing protein 41 antibody, LRRC41 antibody, lrrc41 antibody, LOC100550348 antibody, Lrrc41 antibody

Background:

Synonyms: elongin BC interacting leucine rich repeat protein, Leucine rich repeat containing 41, Leucine rich repeat containing protein 41, MUF1, PP7759, LRC41_HUMAN.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gene ID: 10489