UBE2E2 antibody (AA 1-100) (AbBy Fluor® 647)
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- Target See all UBE2E2 Antibodies
- UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))
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Binding Specificity
- AA 1-100
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UBE2E2 antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Rat
- Predicted Reactivity
- Mouse,Cow,Sheep
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human UBE2E2
- Isotype
- IgG
- Top Product
- Discover our top product UBE2E2 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- UBE2E2 (Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2))
- Alternative Name
- UBE2E2 (UBE2E2 Products)
- Synonyms
- ubch8 antibody, UBCH8 antibody, wu:fb38h07 antibody, zgc:92467 antibody, BC016265 antibody, ubiquitin-conjugating enzyme E2E 2 antibody, ubiquitin conjugating enzyme E2E 2 L homeolog antibody, ubiquitin conjugating enzyme E2E 2 antibody, Ube2e2 protein antibody, ubiquitin conjugating enzyme E2 E2 antibody, UBE2E2 antibody, ube2e2.L antibody, ube2e2 antibody, Ube2e2 antibody
- Background
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Synonyms: UB2E2_HUMAN, UBC4/5 homolog yeast, UBCH 8, UbcH8, Ube2e2, Ubiquitin carrier protein E2, Ubiquitin conjugating enzyme E2 E2, Ubiquitin conjugating enzyme E2E 2 homologous to yeast UBC4/5, Ubiquitin conjugating enzyme E2E 2 UBC4/5 homolog yeast, Ubiquitin conjugating enzyme E2E 2, Ubiquitin protein ligase E2, Ubiquitin-conjugating enzyme E2 E2, Ubiquitin-protein ligase E2.
Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). The first step in the ubiquitination process requires the ATP-dependent activation of the ubiquitin C-terminus and the assembly of multi-ubiquitin chains by the E1 enzyme. The ubiquitin chain is then conjugated to the E2 enzyme to generate an intermediate ubiquitin-E2 complex. The E3 enzyme then catalyzes the transfer of ubiquitin from E2 to the appropriate protein substrate, thereby targeting that substrate for degradation. A wide range of enzymes facilitate this proteolytic ubiquitin pathway, one of which is UBE2E2 (also known as UBCH8 in human), which functions as an E2 enzyme and catalyzes the ATP-dependent covalent attachment of ubiquitin to target proteins, thereby playing an important role in protein degradation.
- Gene ID
- 7325
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