RDH13 antibody (AA 101-200) (Biotin)

Catalog No. ABIN1398475

Product Details anti-RDH13 Antibody (Biotin)

Target: RDH13 (Retinol Dehydrogenase 13 (All-Trans and 9-Cis) (RDH13))

Binding Specificity: AA 101-200

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RDH13 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RDH13

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RDH13

Target: RDH13 (Retinol Dehydrogenase 13 (All-Trans and 9-Cis) (RDH13))

Alternative Name: RDH13 (RDH13 Products)

Synonyms: 8430425D21Rik antibody, SDR7C3 antibody, retinol dehydrogenase 13 antibody, retinol dehydrogenase 13 (all-trans and 9-cis) antibody, Rdh13 antibody, RDH13 antibody

Background:

Synonyms: RDH13, RDH13_HUMAN, Retinol dehydrogenase 13 all trans and 9 cis, Retinol dehydrogenase 13 all trans/9 cis, Retinol dehydrogenase 13.

Background: RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.

Gene ID: 112724