FAM82A1 antibody (AA 261-360) (Biotin)

Catalog No. ABIN1398355

Product Details anti-FAM82A1 Antibody (Biotin)

Target: FAM82A1 (RMDN2) (Regulator of Microtubule Dynamics 2 (RMDN2))

Binding Specificity: AA 261-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM82A1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM82A1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FAM82A1

Target: FAM82A1 (RMDN2) (Regulator of Microtubule Dynamics 2 (RMDN2))

Alternative Name: FAM82A1 (RMDN2 Products)

Synonyms: FAM82A antibody, FAM82A1 antibody, PRO34163 antibody, PYST9371 antibody, RMD-2 antibody, RMD2 antibody, RMD4 antibody, regulator of microtubule dynamics 2 antibody, RMDN2 antibody

Background:

Synonyms: BLOCK18, FAM82A, Fam82a1, Family with sequence similarity 82 member A, Family with sequence similarity 82, member A1, hRMD 2, hRMD 4, hRMD-2, hRMD4, MGC33318, Microtubule associated protein, Protein FAM82A1, Regulator of microtubule dynamics, Regulator of microtubule dynamics protein 2, RMD 2, RMD-2, RMD2, RMD2_HUMAN.

Background: The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The FAM82A gene product has been provisionally designated FAM82A pending further characterization.