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DPYS antibody (AA 121-220) (AbBy Fluor® 488)

DPYS Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1398220
  • Target See all DPYS Antibodies
    DPYS (Dihydropyrimidinase (DPYS))
    Binding Specificity
    • 14
    • 8
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 121-220
    Reactivity
    • 46
    • 16
    • 14
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 46
    • 2
    Rabbit
    Clonality
    • 47
    • 1
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DPYS antibody is conjugated to AbBy Fluor® 488
    Application
    • 39
    • 21
    • 17
    • 12
    • 12
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DHP/Dihydropyrimidinase
    Isotype
    IgG
    Top Product
    Discover our top product DPYS Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    DPYS (Dihydropyrimidinase (DPYS))
    Alternative Name
    Dihydropyrimidinase (DPYS Products)
    Synonyms
    DHP antibody, DHPase antibody, 1200017I10Rik antibody, 1300004I01Rik antibody, dhp antibody, dihydropyrimidinase antibody, dihydropyrimidinase L homeolog antibody, DPYS antibody, Dpys antibody, Jann_1488 antibody, hydA antibody, h16_A3075 antibody, Veis_0725 antibody, AZC_1966 antibody, M446_2543 antibody, RSKD131_3628 antibody, Vapar_5601 antibody, Rleg_5687 antibody, LOC9307588 antibody, EIO_3239 antibody, blr3333 antibody, BAV0676 antibody, hyuA antibody, CtCNB1_2936 antibody, dpyS antibody, Pat9b_1914 antibody, dpys antibody, dpys.L antibody
    Background

    Synonyms: DHP, DHPase, Dihydropyrimidinase, Dihydropyrimidine amidohydrolase, Dpys, DPYS_HUMAN, Hydantoinase.

    Background: Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyzes the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.Tissue specificity:Liver and kidney.Involvement in disease:Defects in DPYS are the cause of dihydropyrimidinase deficiency (DHPD). DHPD is an autosomal recessive disorder characterized by dihydropyrimidinuria and associated with a variable clinical phenotype: epileptic or convulsive attacks, dysmorphic features and severe developmental delay, and congenital microvillous atrophy.

    Gene ID
    1807
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