ITPR3 antibody (AA 21-120) (AbBy Fluor® 647)
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- Target See all ITPR3 Antibodies
- ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))
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Binding Specificity
- AA 21-120
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ITPR3 antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ITPR3
- Isotype
- IgG
- Top Product
- Discover our top product ITPR3 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))
- Alternative Name
- Itpr3 (ITPR3 Products)
- Synonyms
- Ip3r3 antibody, Itpr-3 antibody, IP3R antibody, IP3R3 antibody, IP3R3X antibody, inositol 1,4,5-triphosphate receptor 3 antibody, inositol 1,4,5-trisphosphate receptor type 3 antibody, inositol 1,4,5-trisphosphate receptor, type 3 antibody, Itpr3 antibody, ITPR3 antibody
- Background
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Synonyms: IP3R-III, IP3 receptor isoform 3, 4 antibody 5-trisphosphate receptor, 5-trisphosphate receptor type 3, FLJ36205, Inositol 1, Inositol 1,4,5 trisphosphate receptor type 3, IP3 receptor, IP3R 3, IP3R, IP3R3, ITPR 3, ITPR3, ITPR3_HUMAN, Type 3 inositol 1, Type 3 inositol 1,4,5 trisphosphate receptor, Type 3 InsP3 receptor.
Background: Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
- Gene ID
- 3710
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, BCR Signaling
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