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HIV-1 Gag antibody (AA 351-450) (AbBy Fluor® 350)

GAG_HIV Reactivity: Human Immunodeficiency Virus (HIV), Virus IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN1397216
  • Target See all HIV-1 Gag (GAG_HIV) products
    HIV-1 Gag (GAG_HIV) (HIV-1 Gag Polyprotein (GAG_HIV))
    Binding Specificity
    • 14
    • 1
    • 1
    AA 351-450
    Reactivity
    Human Immunodeficiency Virus (HIV), Virus
    Host
    • 18
    • 13
    • 4
    Rabbit
    Clonality
    • 22
    • 13
    Polyclonal
    Conjugate
    • 11
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIV-1 Gag antibody is conjugated to AbBy Fluor® 350
    Application
    • 20
    • 20
    • 12
    • 12
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Specificity
    This antibody will recognize the full Gag protein and Nucleocapsid protein p7 after cleavage
    Cross-Reactivity
    Virus
    Cross-Reactivity (Details)
    HIV
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from HIV1 Nucleocapsid protein p7
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HIV-1 Gag (GAG_HIV) (HIV-1 Gag Polyprotein (GAG_HIV))
    Alternative Name
    HIV1 Gag Protein (GAG_HIV Products)
    Target Type
    Viral Protein
    Background

    Synonyms: HIV1 Pr55Gag, Human immunodeficiency virus 1, Gag protein, Nucleocapsid protein p7,

    Background: HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. p55 is digested by HIV1 protease into intermediate products p41 and p15. p41 is further digested into matrix protein p17 and capsid protein p24. Likewise, p15 is further digested into nucleocapsid protein p7 and to p6 and p1.

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