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ENPP1 antibody (AA 41-140) (AbBy Fluor® 350)

ENPP1 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN1397030
  • Target See all ENPP1 Antibodies
    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
    Binding Specificity
    • 14
    • 14
    • 14
    • 14
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 41-140
    Reactivity
    • 43
    • 34
    • 11
    • 7
    • 4
    Mouse
    Host
    • 74
    • 5
    • 2
    Rabbit
    Clonality
    • 78
    • 3
    Polyclonal
    Conjugate
    • 22
    • 13
    • 12
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ENPP1 antibody is conjugated to AbBy Fluor® 350
    Application
    • 66
    • 35
    • 13
    • 13
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ENPP1
    Isotype
    IgG
    Top Product
    Discover our top product ENPP1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
    Alternative Name
    ENPP1 (ENPP1 Products)
    Synonyms
    ENPP1 antibody, si:ch211-142e24.2 antibody, zgc:136238 antibody, ARHR2 antibody, M6S1 antibody, NPP1 antibody, NPPS antibody, PC-1 antibody, PCA1 antibody, PDNP1 antibody, 4833416E15Rik antibody, AI428932 antibody, C76301 antibody, CD203c antibody, E-NPP1 antibody, Ly-41 antibody, Npps antibody, Pca antibody, Pca-1 antibody, Pdnp1 antibody, ttw antibody, twy antibody, Pc1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 L homeolog antibody, ENPP1 antibody, enpp1 antibody, enpp1.L antibody, Enpp1 antibody
    Background

    Synonyms: M6S1, NPP1, NPPS, PC-1, PCA1, ARHR2, COLED, PDNP1, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, E-NPP 1, Membrane component chromosome 6 surface marker 1, Phosphodiesterase I/nucleotide pyrophosphatase 1, Plasma-cell membrane glycoprotein PC-1, ENPP1, PC1

    Background: By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.

    Gene ID
    5167
    UniProt
    P22413
    Pathways
    Regulation of Carbohydrate Metabolic Process
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