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Keratan Sulfate antibody (AA 251-350) (AbBy Fluor® 350)

KS Reactivity: Mouse, Rat WB, FACS, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN1396928
  • Target See all Keratan Sulfate (KS) Antibodies
    Keratan Sulfate (KS)
    Binding Specificity
    AA 251-350
    Reactivity
    • 16
    • 16
    • 3
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 15
    • 3
    Rabbit
    Clonality
    • 15
    • 3
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Keratan Sulfate antibody is conjugated to AbBy Fluor® 350
    Application
    • 18
    • 14
    • 12
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Keratan Sulfate
    Isotype
    IgG
    Top Product
    Discover our top product KS Primary Antibody
  • Application Notes
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Keratan Sulfate (KS)
    Alternative Name
    Keratan Sulfate (KS Products)
    Background

    Synonyms: Carbohydrate chondroitin 6 keratan sulfotransferase 1, Carbohydrate chondroitin 6 keratan sulfotransferase, Carbohydrate keratan sulfate Gal 6 sulfotransferase, Carbohydrate keratan sulfate Gal 6 sulfotransferase 1, Carbohydrate sulfotransferase 1, CHST1, EC 2.8.2.21, Galactose N acetylglucosamine N acetylglucosamine 6 O sulfotransferase 1, GST 1 antibody Keratan sulfate Gal 6 sulfotransferase, KS6ST, KSGAL6ST, KSST.

    Background: Catalyzes the transfer of sulfate to position 6 of galactose residues of keratan. It has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal galactose residues are sulfated. It also may function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. It participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains. Whereas chondroitin sulfate is widely distributed throughout the body, keratan sulfate is primarily expressed in cartilage (joints, trachea, intervertebral discs) and cornea.

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