beta 2 Defensin antibody (AA 24-64) (AbBy Fluor® 488)

Catalog No. ABIN1396197

Product Details anti-beta 2 Defensin Antibody (AbBy Fluor® 488)

Target: beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))

Binding Specificity: AA 24-64

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta 2 Defensin antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human beta 2 Defensin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for beta 2 Defensin

Target: beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))

Abstract: BD-2 Products

Synonyms: BD-2 antibody, BD-4 antibody, DEFB-4 antibody, hBD-4 antibody, BD2 antibody, DEFB2 antibody, defensin beta 2 antibody, defensin beta 104B antibody, beta defensin 2 antibody, Defb2 antibody, DEFB104B antibody, SBD2 antibody

Background:

Synonyms: BD-2, SAP1, DEFB2, DEFB4, HBD-2, DEFB-2, DEFB12, Beta-defensin 4A, Beta-defensin 2, Defensin, beta 2, Skin-antimicrobial peptide 1, DEFB4A

Background: Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways

Gene ID: 1673

UniProt: O15263