ZNF131 antibody (AA 351-460) (Biotin)

Catalog No. ABIN1395943

Product Details anti-ZNF131 Antibody (Biotin)

Target: ZNF131 (Zinc Finger Protein 131 (ZNF131))

Binding Specificity: AA 351-460

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF131 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF131

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ZNF131

Target: ZNF131 (Zinc Finger Protein 131 (ZNF131))

Alternative Name: ZNF131 (ZNF131 Products)

Synonyms: zgc:66182 antibody, zgc:77600 antibody, ZBTB35 antibody, pHZ-10 antibody, 2610109I01Rik antibody, AW558871 antibody, Znf131 antibody, zinc finger protein 131 antibody, zinc finger protein 131 S homeolog antibody, znf131 antibody, znf131.S antibody, ZNF131 antibody, Zfp131 antibody

Background:

Synonyms: pH Z 10, pH Z10, Zinc finger protein 131, ZN131_HUMAN, ZNF 131, Znf131.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF131 (Zinc finger protein 131) is a 623 amino acid nuclear protein that contains one BTB (POZ) domain and six C2H2-type zinc fingers. With predominant expression found in brain, it is likely that ZNF131 plays a role as a transcription regulator during development and organogenesis of the adult central nervous system. ZNF131 also represses ER Alpha (Estrogen receptor alpha)-mediated transactivation by interrupting ER?binding to the estrogen-response element. There are two isoforms of ZNF131 that are produced as a result of alternative splicing events.

Gene ID: 7690