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Fibrillin 2 antibody (AA 1001-1200) (AbBy Fluor® 488)

FBN2 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1395538
  • Target See all Fibrillin 2 (FBN2) Antibodies
    Fibrillin 2 (FBN2)
    Binding Specificity
    • 14
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1001-1200
    Reactivity
    • 28
    • 5
    • 1
    • 1
    • 1
    Human
    Host
    • 27
    • 3
    • 2
    Rabbit
    Clonality
    • 29
    • 3
    Polyclonal
    Conjugate
    • 14
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Fibrillin 2 antibody is conjugated to AbBy Fluor® 488
    Application
    • 15
    • 12
    • 12
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Fibrillin 2
    Isotype
    IgG
    Top Product
    Discover our top product FBN2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Fibrillin 2 (FBN2)
    Alternative Name
    Fibrillin 2 (FBN2 Products)
    Synonyms
    CCA antibody, DA9 antibody, BC063774 antibody, Fib-2 antibody, mKIAA4226 antibody, sne antibody, sy antibody, FBN2 antibody, fibrillin 2 antibody, fibrillin 3 antibody, FBN2 antibody, Fbn2 antibody, FBN3 antibody
    Background

    Synonyms: CCA, congenital contractural arachnodactyly Marfanoid-like, DA9, FBN2, FBN2_HUMAN, fibrillin 2 congenital contractural arachnodactyly, Fibrillin-2.

    Background: Extracellular glycoproteins fibrillin-1 and -2 are major components of connective tissue microfibrils. Fibrillin-2 containing microfibrils regulate the early process of elastic fiber assembly in tissue. Mutations in the fibrillin-2 gene resulting in impaired assembly of fibrillin-2 may lead to molecular congenital contractural arachnodactyly. Fibrillin-2 constitutes the backbone of microfibrils which insert directly into the lamina densa of basement membranes. Epithelial cells primarily deposit fibrillin into the extracellular matrix in a nonfibrillar form. Mutations in the 8-cysteine motif of Fibrillin-2 alters its binding to microfibril-associated glycoprotein-1 (MAGP-1), which may increase the severity of congenital contractural arachnodactyly.

    Pathways
    Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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