5HT1D antibody (AA 2-110) (AbBy Fluor® 647)

Catalog No. ABIN1394844

Product Details anti-5HT1D Antibody (AbBy Fluor® 647)

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Binding Specificity: AA 2-110

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 5HT1D antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT1D Receptor/SR-1D

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for 5HT1D

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Alternative Name: 5HT1D Receptor/SR-1D (HTR1D Products)

Synonyms: AI853647 antibody, Gpcr14 antibody, Htr1db antibody, 5-HT1D antibody, HT1DA antibody, HTR1DA antibody, HTRL antibody, RDC4 antibody, 5HT1D antibody, 5-HT-1D antibody, 5-hydroxytryptamine (serotonin) receptor 1D antibody, 5-hydroxytryptamine receptor 1D antibody, Htr1d antibody, HTR1D antibody

Background:

Synonyms: 5-hydroxytryptamine receptor 1D, 5-HT-1D, 5-HT1D, Serotonin 1D alpha receptor, 5-HT-1D-alpha, Serotonin receptor 1D

Background: The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Gene ID: 3352

UniProt: P28221

Pathways: JAK-STAT Signaling