Trace Amine Associated Receptor 8 (TAAR8) (AA 51-150) antibody (Biotin)

Catalog No. ABIN1394713

Product Details

Target: Trace Amine Associated Receptor 8 (TAAR8)

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 102

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: Trace Amine Associated Receptor 8 (TAAR8)

Alternative Name: GPR102/TAAR8 (TAAR8 Products)

Synonyms: GPR102 antibody, TA5 antibody, TAR5 antibody, TRAR5 antibody, TaR-5 antibody, TaR-8 antibody, trace amine associated receptor 8 antibody, TAAR8 antibody

Background:

Synonyms: G protein coupled receptor 102, G-protein coupled receptor 102, GPR102, TA5, TAAR8, TAAR8_HUMAN, TaR-5, TaR-8, TAR5, Trace amine assiciated receptor 8, Trace amine receptor 5, Trace amine receptor 8, Trace amine-associated receptor 8, TRAR5, GPCR GPR102.

Background: Trace amines are endogenous molecules structurally related to classical biogenic amines that are linked to psychiatric conditions. A family of G-protein coupled receptors referred to as trace-amine-associated receptors (TAAR) are activated by trace amines and are present in very low levels in mammalian tissue. TaRs contain several structural features that are similar to the rhodopsin -adrenergic receptor superfamily, including the positions of the seven transmembrane regions that provide common ligand-binding pockets as well as the short N- and C-terminal domains. TAAR proteins are potential targets for drugs of abuse, such as amphetamine and MDMA, as well as neuropsychiatric disorders including schizophrenia, depression, and attention deficit disorder.