GPR125 antibody (AA 422-530) (FITC)

Catalog No. ABIN1394702

Product Details anti-GPR125 Antibody (FITC)

Target: GPR125 (G Protein-Coupled Receptor 125 (GPR125))

Binding Specificity: AA 422-530

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR125 antibody is conjugated to FITC

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR125

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GPR125

Target: GPR125 (G Protein-Coupled Receptor 125 (GPR125))

Alternative Name: GPR125 (GPR125 Products)

Synonyms: PGR21 antibody, TEM5L antibody, 3830613O22Rik antibody, AU044632 antibody, Tem5-like antibody, GPR125 antibody, Gpr125 antibody, adhesion G protein-coupled receptor A3 antibody, adhesion G protein-coupled receptor A3-like antibody, ADGRA3 antibody, Adgra3 antibody, ADGRA3L antibody, adgra3 antibody

Background:

Synonyms: FLJ38547, G protein coupled receptor 125, PGR21, Probable G protein coupled receptor 125 precursor, TEM5 like, TEM5L, GP125_HUMAN, GPCR125.

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events.