KIAA0562 antibody (AA 451-550) (AbBy Fluor® 488)

Catalog No. ABIN1394602

Product Details anti-KIAA0562 Antibody (AbBy Fluor® 488)

Target: KIAA0562

Binding Specificity: AA 451-550

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIAA0562 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CEP104/KIAA0562

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KIAA0562

Target: KIAA0562

Alternative Name: CEP104/KIAA0562 (KIAA0562 Products)

Synonyms: KIAA0562 antibody, glybp antibody, kiaa0562 antibody, A930027E11 antibody, AI115523 antibody, Kiaa0562 antibody, mKIAA0562 antibody, GlyBP antibody, centrosomal protein 104 antibody, centrosomal protein 104kDa antibody, CEP104 antibody, cep104 antibody, Cep104 antibody

Background:

Synonyms: CE104_HUMAN, Centrosomal protein of 104 kDa, Cep104, GlyBP, Glycine Binding Protein, glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein, KIAA0562, LOC246295.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The KIAA0562 gene product has been provisionally designated KIAA0562 pending further characterization.