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Chromosome 12 Open Reading Frame 52 (C12orf52) (AA 51-150) antibody (Biotin)

C12orf52 Reactivity: Human ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1394245
  • Target See all Chromosome 12 Open Reading Frame 52 (C12orf52) Antibodies
    Chromosome 12 Open Reading Frame 52 (C12orf52)
    Binding Specificity
    • 14
    • 8
    • 8
    • 7
    AA 51-150
    Reactivity
    Human
    Host
    • 29
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biotin
    Application
    • 15
    • 14
    • 13
    • 13
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    Human,Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RITA/C12orf52
    Isotype
    IgG
    Top Product
    Discover our top product C12orf52 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    Chromosome 12 Open Reading Frame 52 (C12orf52)
    Alternative Name
    RITA/C12orf52 (C12orf52 Products)
    Synonyms
    RITA antibody, C12orf52 antibody, AI853657 antibody, C86297 antibody, Rita antibody, RBPJ interacting and tubulin associated 1 antibody, RBPJ interacting and tubulin associated 1 L homeolog antibody, RITA1 antibody, rita1.L antibody, Rita1 antibody
    Background

    Synonyms: C12orf52, Chromosome 12 open reading frame 52, RBPJ-interacting and tubulin-associated protein, RITA, RITA_HUMAN.

    Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization.

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