Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ITM2C antibody (AA 3-88) (FITC)

ITM2C Reactivity: Human WB, IF (p), IF (cc) Host: Rabbit Polyclonal FITC
Catalog No. ABIN1393748
  • Target See all ITM2C Antibodies
    ITM2C (Integral Membrane Protein 2C (ITM2C))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-88
    Reactivity
    • 35
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 2
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITM2C antibody is conjugated to FITC
    Application
    • 33
    • 17
    • 12
    • 12
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ITM2C
    Isotype
    IgG
    Top Product
    Discover our top product ITM2C Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ITM2C (Integral Membrane Protein 2C (ITM2C))
    Alternative Name
    ITM2C (ITM2C Products)
    Synonyms
    3110038L02Rik antibody, BRI3 antibody, Bricd2c antibody, E25 antibody, E25C antibody, ITM3 antibody, BRICD2C antibody, fj35c02 antibody, itm2c antibody, wu:fj35c02 antibody, zgc:66349 antibody, wu:fj52a04 antibody, zgc:92783 antibody, integral membrane protein 2C antibody, integral membrane protein 2Cb antibody, integral membrane protein 2Ca antibody, Itm2c antibody, ITM2C antibody, itm2cb antibody, itm2ca antibody
    Background

    Synonyms: BRI3, BRICD2C, BRICHOS domain containing 2C, Cerebral protein 14, CT-BRI3, E25, E25C , Integral membrane protein 2C, Integral membrane protein 3, Itm2c, ITM2C_HUMAN, ITM3 antibodyNPD018, Transmembrane protein BRI3.

    Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

    Gene ID
    81618
    UniProt
    Q9NQX7
You are here:
Support