HS6ST1 antibody (Biotin)

Catalog No. ABIN1393717

Product Details anti-HS6ST1 Antibody (Biotin)

Target: HS6ST1 (Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HS6ST1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HS6ST1

Isotype: IgG

Application Details

Application Notes: WB(1:100-1000), IHC-P(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for HS6ST1

Target: HS6ST1 (Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1))

Alternative Name: Hs6st1 (HS6ST1 Products)

Synonyms: HH15 antibody, HS6ST antibody, 6Ost1 antibody, CHS6ST-1 antibody, 6OST1 antibody, HS6ST-1 antibody, hs6st1 antibody, zgc:110038 antibody, heparan sulfate 6-O-sulfotransferase 1 antibody, heparan sulfate 6-O-sulfotransferase 1a antibody, heparan sulfate 6-O-sulfotransferase 1b antibody, HS6ST1 antibody, Hs6st1 antibody, hs6st1a antibody, hs6st1b antibody

Background:

Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate (HS) biosynthetic enzymes. HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), also known as HS6ST, is a 411 amino acid single-pass type II membrane protein that exists as multiple alternatively spliced isoforms and belongs to the sulfotransferase 6 family. Expressed in fetal brain, HS6ST1 functions as a 6-O-sulfation enzyme that specifically catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the N-sulfoglucosamine residue (GlcNS) HS. HS6ST1 is subject to post-translational N-glycosylation and is encoded by a functional gene on human chromosome 2 and a pseudogene on human chromosome 1 (known as LOC728969).

Synonyms: 6OST 1, 6OST1, DKFZp547H098, FLJ25392, H6 ST1, H6ST 1, H6ST1_HUMAN, Heparan sulfate 6 O sulfotransferase 1, Heparan sulfate 6 sulfotransferase, Heparan sulphate 6 O sulphotransferase 1, Heparan-sulfate 6-O-sulfotransferase 1, HS6 ST1, HS6ST 1, HS6ST , HS6ST-1, HS6ST1, MGC116899, MGC116901.

Pathways: Glycosaminoglycan Metabolic Process