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DOK4 antibody (AA 22-98) (AbBy Fluor® 488)

DOK4 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1393552
  • Target See all DOK4 Antibodies
    DOK4 (Docking Protein 4 (DOK4))
    Binding Specificity
    • 14
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    AA 22-98
    Reactivity
    • 49
    • 17
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 49
    Rabbit
    Clonality
    • 49
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOK4 antibody is conjugated to AbBy Fluor® 488
    Application
    • 34
    • 17
    • 17
    • 12
    • 12
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DOK4
    Isotype
    IgG
    Top Product
    Discover our top product DOK4 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    DOK4 (Docking Protein 4 (DOK4))
    Alternative Name
    DOK4 (DOK4 Products)
    Synonyms
    DOK4 antibody, docking protein 4 antibody, DOK4 antibody, Dok4 antibody
    Background

    Synonyms: docking protein 4, Downstream of tyrosine kinase 4, FLJ10488, DOK4_HUMAN.

    Background: The downstream of kinase family (Dok-1-7) are members of a class of docking proteins that interact with receptor tyrosine kinases and, via this interaction, mediate biological responses within the body. Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.

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