CHURC1 antibody (AA 11-112) (Biotin)

Catalog No. ABIN1393519

Product Details anti-CHURC1 Antibody (Biotin)

Target: CHURC1 (Churchill Domain Containing 1 (CHURC1))

Binding Specificity: AA 11-112

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHURC1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHURC1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CHURC1

Target: CHURC1 (Churchill Domain Containing 1 (CHURC1))

Alternative Name: CHURC1 (CHURC1 Products)

Synonyms: C14orf52 antibody, chch antibody, 1700030P15Rik antibody, My015 antibody, chch-a antibody, churchill antibody, churchill domain containing 1 antibody, churchill domain containing 1 S homeolog antibody, CHURC1 antibody, Churc1 antibody, churc1.S antibody

Background:

Synonyms: CHURC-1, C14orf52, CHCH, CHURC 1, Churchill domain containing 1, FLJ33064, My015, Protein Churchill, CHUR_HUMAN.

Background: CHURC1 is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF signaling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.