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ZFHX3 antibody (AA 301-400) (Biotin)

ZFHX3 Reactivity: Rat ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1393429
  • Target See all ZFHX3 Antibodies
    ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
    Binding Specificity
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reactivity
    • 16
    • 15
    • 11
    Rat
    Host
    • 27
    • 2
    • 1
    Rabbit
    Clonality
    • 29
    • 1
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZFHX3 antibody is conjugated to Biotin
    Application
    • 13
    • 13
    • 9
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ATBF1
    Isotype
    IgG
    Top Product
    Discover our top product ZFHX3 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
    Alternative Name
    ATBF1 (ZFHX3 Products)
    Synonyms
    ZFHX3 antibody, ATBF1 antibody, ATBT antibody, ZNF927 antibody, A230102L03Rik antibody, Atbf1 antibody, WBP9 antibody, mKIAA4228 antibody, RGD1560268 antibody, zax-2 antibody, zinc finger homeobox 3 antibody, AT-binding transcription factor1 antibody, zfhx3 antibody, ZFHX3 antibody, ATBF1/ZFHX4b antibody, Zfhx3 antibody
    Background

    Synonyms: Alpha fetoprotein enhancer binding protein, AT binding transcription factor 1, AT mot binding factor, ATBT, ZFHX3, ZFHX3_HUMAN.

    Background: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (13). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).

    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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