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SPG21 antibody (AA 151-250) (AbBy Fluor® 555)

SPG21 Reactivity: Human WB, IF (p), IF (cc) Host: Rabbit Polyclonal AbBy Fluor® 555
Catalog No. ABIN1393307
  • Target See all SPG21 Antibodies
    SPG21 (Spastic Paraplegia 21 (SPG21))
    Binding Specificity
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 151-250
    Reactivity
    • 26
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 23
    • 3
    Rabbit
    Clonality
    • 24
    • 2
    Polyclonal
    Conjugate
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPG21 antibody is conjugated to AbBy Fluor® 555
    Application
    • 19
    • 12
    • 12
    • 10
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SPG21
    Isotype
    IgG
    Top Product
    Discover our top product SPG21 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SPG21 (Spastic Paraplegia 21 (SPG21))
    Alternative Name
    SPG21 (SPG21 Products)
    Synonyms
    ACP33 antibody, GL010 antibody, MAST antibody, BM-019 antibody, C78576 antibody, D9Wsu18e antibody, Maspardin antibody, wu:fd07h02 antibody, zgc:73091 antibody, SPG21, maspardin antibody, spastic paraplegia 21 (autosomal recessive, Mast syndrome) antibody, SPG21, maspardin S homeolog antibody, SPG21 antibody, Spg21 antibody, spg21.S antibody, spg21 antibody
    Background

    Synonyms: Acid cluster protein 33, ACP33, BM019, BM-019, GL010, MAST, Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21 antibody, SPG21_HUMAN.

    Background: Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome.

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