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PQBP1 antibody (AA 185-265) (AbBy Fluor® 350)

PQBP1 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN1393107
  • Target See all PQBP1 Antibodies
    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
    Binding Specificity
    • 14
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 185-265
    Reactivity
    • 34
    • 9
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    Human
    Host
    • 32
    • 3
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PQBP1 antibody is conjugated to AbBy Fluor® 350
    Application
    • 29
    • 12
    • 12
    • 11
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PQBP1
    Isotype
    IgG
    Top Product
    Discover our top product PQBP1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
    Alternative Name
    PQBP1 (PQBP1 Products)
    Synonyms
    PQBP1 antibody, MRX55 antibody, MRXS3 antibody, MRXS8 antibody, NPW38 antibody, RENS1 antibody, SHS antibody, PQBP-1 antibody, Sfc2 antibody, npw38 antibody, polyglutamine binding protein 1 antibody, PQBP1 antibody, Pqbp1 antibody
    Background

    Synonyms: 38 kDa nuclear protein containing a WW domain, Mental retardation, X linked 55, MRX55, MRXS3, MRXS8, Npw38, Nuclear protein containing WW domain 38 kD, Polyglutamine binding protein 1, Polyglutamine tract binding protein 1, Polyglutamine tract-binding protein 1, Polyglutamine-binding protein 1, PQBP 1, PQBP-1, PQBP1, PQBP1_HUMAN, RENS1, SHS, Sutherland Haan X linked mental retardation syndrome.

    Background: Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.

    Pathways
    Ribonucleoprotein Complex Subunit Organization
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