NDUFS7 antibody (AA 101-160) (AbBy Fluor® 350)
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- Target See all NDUFS7 Antibodies
- NDUFS7 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 7, 20kDa (NADH-Coenzyme Q Reductase) (NDUFS7))
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Binding Specificity
- AA 101-160
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NDUFS7 antibody is conjugated to AbBy Fluor® 350
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat,Dog,Cow,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NDUFS7
- Isotype
- IgG
- Top Product
- Discover our top product NDUFS7 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- NDUFS7 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 7, 20kDa (NADH-Coenzyme Q Reductase) (NDUFS7))
- Alternative Name
- NDUFS7 (NDUFS7 Products)
- Synonyms
- 1010001M04Rik antibody, CI-20 antibody, CI-20KD antibody, MY017 antibody, PSST antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 7 antibody, NADH:ubiquinone oxidoreductase core subunit S7 antibody, Ndufs7 antibody, NDUFS7 antibody
- Background
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Synonyms: CI 20, CI-20kD, Complex I 20 kDa subunit, Complex I mitochondrial respiratory chain 20 KD subunit, Complex I-20kD, MGC120002, MY017, NADH coenzyme Q reductase, NADH dehydrogenase ubiquinone Fe S protein 7 20 kDa NADH coenzyme Q reductase, NADH dehydrogenase ubiquinone FeS protein 7, 20 kDa NADHcoenzyme Q reductase, NADH dehydrogenase ubiquinone FeS protein7, 20 kDa NADHcoenzyme Q reductase, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, NADH-ubiquinone oxidoreductase 20 kDa subunit, NADH:ubiquinone oxidoreductase PSST subunit, NADHcoenzyme Q reductase, Ndufs7, NDUS7_HUMAN, PSST, PSST subunit.
Background: Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.
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