KCNQ2 antibody (AA 91-150) (AbBy Fluor® 555)
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- Target See all KCNQ2 Antibodies
- KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
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Binding Specificity
- AA 91-150
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KCNQ2 antibody is conjugated to AbBy Fluor® 555
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Application
- Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Sheep,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human KCNQ2
- Isotype
- IgG
- Top Product
- Discover our top product KCNQ2 Primary Antibody
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
- Alternative Name
- KCNQ2 (KCNQ2 Products)
- Synonyms
- BFNC antibody, BFNS1 antibody, EBN antibody, EBN1 antibody, EIEE7 antibody, ENB1 antibody, HNSPC antibody, KCNA11 antibody, KV7.2 antibody, KVEBN1 antibody, KQT2 antibody, Nmf134 antibody, mKQT2.3 antibody, mKQT2.4 antibody, zgc:171872 antibody, potassium voltage-gated channel subfamily Q member 2 antibody, potassium voltage-gated channel, subfamily Q, member 2 antibody, potassium voltage-gated channel subfamily KQT member 2 antibody, potassium voltage-gated channel, KQT-like subfamily, member 2a antibody, KCNQ2 antibody, Kcnq2 antibody, LOC100537363 antibody, kcnq2a antibody
- Background
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Synonyms: BFNC, BFNS1, EBN 1, EBN, EBN1, EIEE7, ENB 1, ENB1, HNSPC, KCNA 11, KCNA11, KCNQ 2, Kcnq2, KCNQ2_HUMAN, KQT like 2, KQT-like 2, KV7.2, KVEBN 1, KVEBN1, KvLQT 2, KvLQT2, Neuroblastoma specic potassium channel alpha subunit KvLQT2, Neuroblastoma specic potassium channel protein, Neuroblastoma specic potassium channel subunit alpha, Neuroblastoma specic potassium channel subunit alpha KvLQT2, Neuroblastoma-specic potassium channel subunit alpha KvLQT2, Potassium voltage gated channel KQT like protein 2, Potassium voltage gated channel KQT like subfamily member 2, Potassium voltage gated channel subfamily KQT member 2, Potassium voltage-gated channel subfamily KQT member 2, Voltage gated potassium channel subunit Kv7.2, Voltage-gated potassium channel subunit Kv7.2.
Background: Epilepsy affects about 0.5 % of the world?s population and has a large genetic component. Epilepsy results from an electrical hyperexcitability in the central nervous system. Potassium channels are important regulators of electrical signaling, determining the firing properties and responsiveness of a variety of neurons. Benign familial neonatal convulsions (BFNC), an autosomal dominant epilepsy of infancy, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes. KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains. Both proteins display a broad distribution within the brain, with expression patterns that largely overlap.
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