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GDAP1 antibody (AA 151-230) (AbBy Fluor® 555)

GDAP1 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 555
Catalog No. ABIN1392959
  • Target See all GDAP1 Antibodies
    GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))
    Binding Specificity
    • 14
    • 2
    • 2
    • 1
    • 1
    AA 151-230
    Reactivity
    • 26
    • 15
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 28
    • 1
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GDAP1 antibody is conjugated to AbBy Fluor® 555
    Application
    • 22
    • 12
    • 12
    • 7
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GDAP1
    Isotype
    IgG
    Top Product
    Discover our top product GDAP1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))
    Alternative Name
    GDAP1 (GDAP1 Products)
    Synonyms
    CMT4 antibody, CMT4A antibody, CMTRIA antibody, ganglioside induced differentiation associated protein 1 antibody, ganglioside-induced differentiation-associated-protein 1 antibody, GDAP1 antibody, Gdap1 antibody
    Background

    Synonyms: Ganglioside induced dferentiation associated protein 1, Ganglioside-induced dferentiation-associated protein 1, GDAP1, GDAP1_HUMAN.

    Background: Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles. Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, two characteristics which are unusual for GST family members. GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage. Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes.

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