APH1B antibody (AA 51-150) (AbBy Fluor® 647)
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- Target See all APH1B (Aph1b) Antibodies
- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
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Binding Specificity
- AA 51-150
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APH1B antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat,Dog,Cow,Sheep,Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Aph-1b
- Isotype
- IgG
- Top Product
- Discover our top product Aph1b Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
- Alternative Name
- Aph-1b (Aph1b Products)
- Synonyms
- APH-1B antibody, PRO1328 antibody, PSFL antibody, TAAV688 antibody, APH-1B' antibody, 2310057K14Rik antibody, Aph1c antibody, aph-1 homolog B, gamma-secretase subunit antibody, aph-1 homolog B, gamma secretase subunit antibody, aph1 homolog B, gamma secretase subunit antibody, APH1B antibody, Aph1b antibody
- Background
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Synonyms: PSFL, APH-1B, PRO1328, TAAV688, Gamma-secretase subunit APH-1B, Aph-1beta, Presenilin-stabilization factor-like, APH1B, UNQ688/PRO1328
Background: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.
- Gene ID
- 83464
- UniProt
- Q8WW43
- Pathways
- Notch Signaling, Neurotrophin Signaling Pathway
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