TWSG1 antibody (AA 151-223) (AbBy Fluor® 350)

Catalog No. ABIN1392267

Product Details anti-TWSG1 Antibody (AbBy Fluor® 350)

Target: TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))

Binding Specificity: AA 151-223

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWSG1 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TWSG1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TWSG1

Target: TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))

Alternative Name: TWSG1 (TWSG1 Products)

Synonyms: TWSG1 antibody, TSG antibody, DKFZp469J051 antibody, 1810013J15Rik antibody, 9030422N06Rik antibody, AW552143 antibody, D17Ertd403e antibody, Tsg antibody, Twg antibody, fi23f01 antibody, tsg antibody, tsga antibody, twsg1 antibody, wu:fi23f01 antibody, twsg antibody, tsg1 antibody, tsgb antibody, ztsg1 antibody, twisted gastrulation BMP signaling modulator 1 antibody, twisted gastrulation homolog 1 (Drosophila) antibody, twisted gastrulation BMP signaling modulator 1a antibody, twisted gastrulation BMP signaling modulator 1 S homeolog antibody, twisted gastrulation BMP signaling modulator 1 L homeolog antibody, twisted gastrulation BMP signaling modulator 1b antibody, TWSG1 antibody, Twsg1 antibody, twsg1a antibody, twsg1.S antibody, twsg1.L antibody, twsg1b antibody

Background:

Synonyms: PSEC0250, TSG, TSG1, twisted gastrulation homolog 1, Twisted gastrulation protein, TWSG1_HUMAN.

Background: Twisted Gastrulation Protein 1(TWSG1) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins thereby preventing BMPs from binding to their receptors. It can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.